Although follicular lymphoma (FL) often responds well to initial therapy, many patients will relapse, and a considerable proportion of patients experience disease progression within 24 months. In this activity, Drs. Nastoupil and Diefenbach address the recent advances in FL-directed CAR T-cell therapies, bispecific antibodies (BsAbs), and antibody-drug conjugates (ADCs). They will also discuss safety and efficacy data from ongoing clinical trials, and how to incorporate recently approved and emerging novel targeted therapies into individualized treatment strategies.

In this activity, Dr. Merryman will address the expanding landscape in the treatment of follicular lymphoma and, along with Dr. Armitage, they will discuss the current standard of care. Dr. Merryman will provide a comprehensive overview of the emerging data in the relapsed setting and discuss the current placement of those agents in the future treatment paradigm with a discussion of potential impact to patient care and outcomes.

In this activity, Dr. Salles will address current and emerging directions in the frontline treatment of follicular lymphoma, he will also discuss recent evidence on emerging therapies and describe implications for current and future practice. To conclude, Dr. Armitage and Dr. Salles examine how to apply these therapies to practice and how to individualize therapy for patients.